Molecular dynamics of MHC genesis unraveled by sequence analysis of the 1,796,938-bp HLA class I region

The intensely studied MHC has become the paradigm for understanding the architectural evolution of vertebrate multigene families. The 4-Mb human MHC (also known as the HLA complex) encodes genes critically involved in the immune response, graft rejection, and disease susceptibility. Here we report t...

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Bibliographic Details
Main Authors: Shiina, Takashi, Tamiya, Gen, Oka, Akira, Takishima, Nobusada, Yamagata, Tetsushi, Kikkawa, Eri, Iwata, Kyoko, Tomizawa, Maiko, Okuaki, Noriko, Kuwano, Yuko, Watanabe, Koji, Fukuzumi, Yasuhito, Itakura, Shoko, Sugawara, Chiyo, Ono, Ayako, Yamazaki, Masaaki, Tashiro, Hiroyuki, Ando, Asako, Ikemura, Toshimichi, Soeda, Eiichi, Kimura, Minoru, Bahram, Seiamak, Inoko, Hidetoshi
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC23939/
https://ncbi.nlm.nih.gov/pubmed/10557312
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