Fluorescence resonance energy transfer in near-infrared fluorescent oligonucleotide probes for detecting protein–DNA interactions

Optical imaging in the near-infrared (NIR) range enables detecting ligand-receptor interactions and enzymatic activity in vivo due to lower scattering and absorption of NIR photons in the tissue. We designed and tested prototype NIR fluorescent oligodeoxyribonucleotide (ODN) reporters that can sense...

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Bibliographic Details
Main Authors: Zhang, Surong, Metelev, Valeri, Tabatadze, David, Zamecnik, Paul C., Bogdanov, Alexei
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393815/
https://ncbi.nlm.nih.gov/pubmed/18337505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800162105
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