Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33

We performed a three-phase genome-wide association study (GWAS) using cases and controls from a genetically isolated population, Ashkenazi Jews (AJ), to identify loci associated with breast cancer risk. In the first phase, we compared allele frequencies of 150,080 SNPs in 249 high-risk, BRCA1/2 muta...

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Autors principals: Gold, Bert, Kirchhoff, Tomas, Stefanov, Stefan, Lautenberger, James, Viale, Agnes, Garber, Judy, Friedman, Eitan, Narod, Steven, Olshen, Adam B., Gregersen, Peter, Kosarin, Kristi, Olsh, Adam, Bergeron, Julie, Ellis, Nathan A., Klein, Robert J., Clark, Andrew G., Norton, Larry, Dean, Michael, Boyd, Jeff, Offit, Kenneth
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393811/
https://ncbi.nlm.nih.gov/pubmed/18326623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800441105
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