NFAR-1 and -2 modulate translation and are required for efficient host defense

We report here that the alternatively spliced nuclear factors associated with double-stranded RNA, NFAR-1 (90 kDa) and -2 (110 kDa), are involved in retaining cellular transcripts in intranuclear foci and can regulate the export of mRNA to the cytoplasm. Furthermore, the NFAR proteins were found to...

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Detalhes bibliográficos
Main Authors: Pfeifer, Ingrid, Elsby, Rachel, Fernandez, Marilyn, Faria, Paula A., Nussenzveig, Daniel R., Lossos, Izidor S., Fontoura, Beatriz M. A., Martin, W. David, Barber, Glen N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393807/
https://ncbi.nlm.nih.gov/pubmed/18337511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711222105
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