Functional analysis of CNK in RAS signaling

Connector enhancer of KSR (CNK) is a multidomain protein required for RAS signaling. Its C-terminal portion (CNK(C-term)) directly binds to RAF. Herein, we show that the N-terminal portion of CNK (CNK(N-term)) strongly cooperates with RAS, whereas CNK(C-term) efficiently blocks RAS- and RAF-dependen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Therrien, Marc, Wong, Allan M., Kwan, Elaine, Rubin, Gerald M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 1999
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC23935/
https://ncbi.nlm.nih.gov/pubmed/10557308
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