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T lymphocytes from mice immunized with irradiated sporozoites eliminate malaria from hepatocytes.

When mice are immunized with radiation-attenuated sporozoites they are solidly protected against sporozoite challenge by an immune response that has been shown to require CD8+ lymphocytes in several strains of mice. The target of this CD8+ T-cell-dependent immunity has not been established. Immune B...

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Detalhes bibliográficos
Main Authors: Hoffman, S. L., Isenbarger, D., Long, G. W., Sedegah, M., Szarfman, A., Mellouk, S., Ballou, W. R.
Formato: Artigo
Idioma:Inglês
Publicado em: World Health Organization 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393038/
https://ncbi.nlm.nih.gov/pubmed/2151270
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