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Oncogenic stimulation recruits cyclin-dependent kinase in the cell cycle start in rat fibroblast
The rat fibroblast NRK cells are transformed reversibly by a combination of growth factors. When stimulated with serum, NRK cells rely on cyclin-dependent kinase 4 (Cdk4) for their S phase entry. However, when stimulated with serum containing oncogenic growth factors, they come to rely on either Cdk...
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Hauptverfasser: | , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
The National Academy of Sciences
1999
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC23924/ https://ncbi.nlm.nih.gov/pubmed/10557297 |
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