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Mast cell migration from the skin to the draining lymph nodes upon UV-irradiation represents a key step in the induction of immune suppression

The UV radiation in sunlight is the primary cause of skin cancer. UV is also immunosuppressive and numerous studies have shown that UV-induced immune suppression is a major risk factor for skin cancer induction. Previous studies demonstrated that dermal mast cells play a critical role in the inducti...

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Bibliographic Details
Main Authors: Byrne, Scott N., Limón-Flores, Alberto Y., Ullrich, Stephen E.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391302/
https://ncbi.nlm.nih.gov/pubmed/18354188
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