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Mutants in DsbB that appear to Redirect Oxidation Through the Disulfide Isomerization Pathway

Disulfide bond formation occurs in secreted proteins in Escherichia coli when the disulfide oxidoreductase DsbA, a soluble periplasmic protein, nonspecifically transfers a disulfide to a substrate protein. The catalytic disulfide of DsbA is regenerated by the inner membrane protein DsbB. To help ide...

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Bibliographic Details
Main Authors: Pan, Jonathan L., Sliskovic, Inga, Bardwell, James C. A.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391272/
https://ncbi.nlm.nih.gov/pubmed/18325532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.01.058
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