Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

The mouse CD8α(+) DC subset excels at cross-presentation of antigen, which can elicit robust CTL responses. A receptor allowing specific antigen targeting to this subset and its equivalent in humans would therefore be useful for the induction of antitumor CTLs. Here, we have characterized a C-type l...

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Bibliographic Details
Main Authors: Sancho, David, Mourão-Sá, Diego, Joffre, Olivier P., Schulz, Oliver, Rogers, Neil C., Pennington, Daniel J., Carlyle, James R., Reis e Sousa, Caetano
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2008
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391066/
https://ncbi.nlm.nih.gov/pubmed/18497879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34584
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