Vasoinhibins prevent retinal vasopermeability associated with diabetic retinopathy in rats via protein phosphatase 2A–dependent eNOS inactivation

Increased retinal vasopermeability contributes to diabetic retinopathy, the leading cause of blindness in working-age adults. Despite clinical progress, effective therapy remains a major need. Vasoinhibins, a family of peptides derived from the protein hormone prolactin (and inclusive of the 16-kDa...

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Détails bibliographiques
Auteurs principaux: García, Celina, Aranda, Jorge, Arnold, Edith, Thébault, Stéphanie, Macotela, Yazmín, López-Casillas, Fernando, Mendoza, Valentín, Quiroz-Mercado, Hugo, Hernández-Montiel, Hebert Luis, Lin, Sue-Hwa, de la Escalera, Gonzalo Martínez, Clapp, Carmen
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391065/
https://ncbi.nlm.nih.gov/pubmed/18497878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34508
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