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Proximity-dependent and proximity-independent trans-splicing in mammalian cells
Most human pre-mRNAs are cis-spliced, removing introns and joining flanking exons of the same RNA molecule. However, splicing of exons present on separate pre-mRNA molecules can also occur. This trans-splicing reaction can be exploited by pre-trans-splicing molecules (PTMs), which are incapable of c...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2390811/ https://ncbi.nlm.nih.gov/pubmed/18441053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.384808 |
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