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Ab initio RNA folding by discrete molecular dynamics: From structure prediction to folding mechanisms

RNA molecules with novel functions have revived interest in the accurate prediction of RNA three-dimensional (3D) structure and folding dynamics. However, existing methods are inefficient in automated 3D structure prediction. Here, we report a robust computational approach for rapid folding of RNA m...

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Hlavní autoři: Ding, Feng, Sharma, Shantanu, Chalasani, Poornima, Demidov, Vadim V., Broude, Natalia E., Dokholyan, Nikolay V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390798/
https://ncbi.nlm.nih.gov/pubmed/18456842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.894608
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