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Specificity of ADAR-mediated RNA editing in newly identified targets
Adenosine deaminases that act on RNA (ADARs) convert adenosines to inosine in both coding and noncoding double-stranded RNA. Deficiency in either ADAR1 or ADAR2 in mice is incompatible with normal life and development. While the ADAR2 knockout phenotype can be attributed to the lack of editing of th...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2390793/ https://ncbi.nlm.nih.gov/pubmed/18430892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.923308 |
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