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Specificity of ADAR-mediated RNA editing in newly identified targets

Adenosine deaminases that act on RNA (ADARs) convert adenosines to inosine in both coding and noncoding double-stranded RNA. Deficiency in either ADAR1 or ADAR2 in mice is incompatible with normal life and development. While the ADAR2 knockout phenotype can be attributed to the lack of editing of th...

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Detalles Bibliográficos
Main Authors: Riedmann, Eva M., Schopoff, Sandy, Hartner, Jochen C., Jantsch, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390793/
https://ncbi.nlm.nih.gov/pubmed/18430892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.923308
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