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Validation of the Reference Tissue Model for Estimation of Dopaminergic D(2)-Like Receptor Binding With [(18) F] (N-Methyl)Benperidol in Humans

PET measurements of dopaminergic D(2)-like receptors may provide important insights into disorders such as Parkinson's disease, schizophrenia, dystonia and Tourette's syndrome. The PET radioligand [(18) F] (N-Methyl)Benperidol ([(18)F]-NMB) has high affinity and selectivity for D(2)-like r...

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Main Authors: Antenor-Dorsey, Jo Ann V., Markham, Joanne, Moerlein, Stephen M., Videen, Tom O., Perlmutter, Joel S.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390782/
https://ncbi.nlm.nih.gov/pubmed/18355689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2007.12.004
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