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Mechanisms of Rad52-Independent Spontaneous and UV-Induced Mitotic Recombination in Saccharomyces cerevisiae

In wild-type diploid cells, heteroallelic recombination between his4A and his4C alleles leads mostly to His(+) gene conversions that have a parental configuration of flanking markers, but ∼22% of recombinants have associated reciprocal crossovers. In rad52 strains, gene conversion is reduced 75-fold...

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Autors principals: Coïc, Eric, Feldman, Taya, Landman, Allison S., Haber, James E.
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390599/
https://ncbi.nlm.nih.gov/pubmed/18458103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.087189
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