Characterization of two functional NKX3.1 binding sites upstream of the PCAN1 gene that are involved in the positive regulation of PCAN1 gene transcription

BACKGROUND: NKX3.1 and PCAN1 are both prostate-specific genes related to prostate development and prostate cancer. So far, little is known about the regulatory mechanisms of the expression of these two genes. In the present study, we found that NKX3.1 upregulated PCAN1 gene transcription in LNCaP pr...

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Main Authors: Liu, Wenwen, Zhang, Pengju, Chen, Weiwen, Yu, Chunxiao, Cui, Fuai, Kong, Feng, Zhang, Jianye, Jiang, Anli
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390571/
https://ncbi.nlm.nih.gov/pubmed/18454873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-45
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