Heme is an effector molecule for iron-dependent degradation of the bacterial iron response regulator (Irr) protein
The bacterial iron response regulator (Irr) protein mediates iron-dependent regulation of heme biosynthesis. Pulse–chase and immunoprecipitation experiments showed that Irr degraded in response to 6 μM iron with a half-life of ≈30 min and that this regulated stability was the principal determinant o...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23899/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10557272/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.23.13056 |
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