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Slow cycling of unphosphorylated myosin is inhibited by calponin, thus keeping smooth muscle relaxed

A key unanswered question in smooth muscle biology is whether phosphorylation of the myosin regulatory light chain (RLC) is sufficient for regulation of contraction, or if thin-filament-based regulatory systems also contribute to this process. To address this issue, the endogenous RLC was extracted...

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Détails bibliographiques
Auteurs principaux: Malmqvist, Ulf, Trybus, Kathleen M., Yagi, Shinobu, Carmichael, Jeff, Fay, Fredric S.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences of the USA 1997
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC23878/
https://ncbi.nlm.nih.gov/pubmed/9207148
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