Relation of 8-ketotrichothecene and zearalenone analog structure to inhibition of mitogen-induced human lymphocyte blastogenesis.

The 50% effective doses of fusarenon X, nivalenol, deoxynivalenol, and 15-acetyldeoxynivalenol required to reduce [3H]thymidine uptake in mitogen-stimulated human lymphocytes by 50% were 18, 72, 140, and 240 ng/ml, respectively. These results indicated that lymphotoxicity of 8-ketotrichothecenes dec...

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Pubblicato in:	Appl Environ Microbiol
Autori principali:	Forsell, J H, Pestka, J J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1985
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238744/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2936303/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.50.5.1304-1307.1985
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