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Palonosetron as an anti-emetic and anti-nausea agent in oncology
Palonosetron (Aloxi(®), Onicit(®), Paloxi(®)) is a second-generation 5-HT(3) receptor antagonist (RA) with an extended half-life of ~40 hours and high binding affinity for the 5-HT(3) receptor that is markedly different from other 5-HT(3) RAs. Phase III trials demonstrate that a single dose of palon...
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Format: | Artigo |
Language: | Inglês |
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Dove Medical Press
2007
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Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2387285/ https://ncbi.nlm.nih.gov/pubmed/18516316 |
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