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Palonosetron as an anti-emetic and anti-nausea agent in oncology

Palonosetron (Aloxi(®), Onicit(®), Paloxi(®)) is a second-generation 5-HT(3) receptor antagonist (RA) with an extended half-life of ~40 hours and high binding affinity for the 5-HT(3) receptor that is markedly different from other 5-HT(3) RAs. Phase III trials demonstrate that a single dose of palon...

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Bibliographic Details
Main Author: Aapro, Matti S
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2387285/
https://ncbi.nlm.nih.gov/pubmed/18516316
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