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in vivo regulation of Yorkie phosphorylation and localization

Yorkie, a transcription factor of the Fat and Hippo signaling pathways, is negatively regulated by the Warts kinase. Here we use Phos-tag gels to characterize Warts-dependent phosphorylation of Yorkie in vivo, and show that Warts promotes phosphorylation of Yorkie at multiple sites. We also show tha...

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Detalles Bibliográficos
Autores principales: Oh, Hyangyee, Irvine, Kenneth D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2387210/
https://ncbi.nlm.nih.gov/pubmed/18256197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.015255
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