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AMP-Activated Protein Kinase Is Essential for Survival in Chronic Hypoxia

This study was undertaken to interrogate cancer cell survival during long-term hypoxic stress. Two systems with relevance to carcinogenesis were employed: fully transformed BJ cells, and a renal carcinoma cell line (786-0). The dynamic of AMPK activity was consistent with a prosurvival role during c...

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Detalhes bibliográficos
Main Authors: Borger, Darrell R., Gavrilescu, L. Cristina, Bucur, Maria C., Ivan, Mircea, DeCaprio, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2387098/
https://ncbi.nlm.nih.gov/pubmed/18359290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.03.056
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