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Select Paramyxoviral V Proteins Inhibit IRF3 Activation by Acting as Alternative Substrates for Inhibitor of κB Kinase ε (IKKe)/TBK1

V accessory proteins from Paramyxoviruses are important in viral evasion of the innate immune response. Here, using a cell survival assay that identifies both inhibitors and activators of interferon regulatory factor 3 (IRF3)-mediated gene induction, we identified select paramyxoviral V proteins tha...

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Detalhes bibliográficos
Main Authors: Lu, Lenette L., Puri, Mamta, Horvath, Curt M., Sen, Ganes C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386944/
https://ncbi.nlm.nih.gov/pubmed/18362155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710089200
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