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Cryptococcal Xylosyltransferase 1 (Cxt1p) from Cryptococcus neoformans Plays a Direct Role in the Synthesis of Capsule Polysaccharides

The opportunistic yeast Cryptococcus neoformans causes serious disease in humans and expresses a prominent polysaccharide capsule that is required for its virulence. Little is known about how this capsule is synthesized. We previously identified a β1,2-xylosyltransferase (Cxt1p) with in vitro enzyma...

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Detalhes bibliográficos
Main Authors: Klutts, J. Stacey, Doering, Tamara L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386922/
https://ncbi.nlm.nih.gov/pubmed/18347023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708927200
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