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IMMOBILIZATION OF ALPHA 1-ACID GLYCOPROTEIN FOR CHROMATOGRAPHIC STUDIES OF DRUG-PROTEIN BINDING II. CORRECTION FOR ERRORS IN ASSOCIATION CONSTANT MEASUREMENTS

A new method for the immobilization of α(1)-acid glycoprotein (AGP) in HPLC columns was recently described for applications such as drug binding studies. Part of this earlier work used self-competition zonal elution studies to measure association equilibrium constants between immobilized AGP and R-...

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Autors principals: Mallik, Rangan, Xuan, Hai, Guiochon, Georges, Hage, David S.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386853/
https://ncbi.nlm.nih.gov/pubmed/18294445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2008.01.035
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