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Mutation detection using ENDO1: Application to disease diagnostics in humans and TILLING and Eco-TILLING in plants
BACKGROUND: Most enzymatic mutation detection methods are based on the cleavage of heteroduplex DNA by a mismatch-specific endonuclease at mismatch sites and the analysis of the digestion product on a DNA sequencer. Important limitations of these methods are the availability of a mismatch-specific e...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2386800/ https://ncbi.nlm.nih.gov/pubmed/18433472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-42 |
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