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Mutation detection using ENDO1: Application to disease diagnostics in humans and TILLING and Eco-TILLING in plants

BACKGROUND: Most enzymatic mutation detection methods are based on the cleavage of heteroduplex DNA by a mismatch-specific endonuclease at mismatch sites and the analysis of the digestion product on a DNA sequencer. Important limitations of these methods are the availability of a mismatch-specific e...

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Detalhes bibliográficos
Main Authors: Triques, Karine, Piednoir, Elodie, Dalmais, Marion, Schmidt, Julien, Le Signor, Christine, Sharkey, Mark, Caboche, Michel, Sturbois, Bénédicte, Bendahmane, Abdelhafid
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386800/
https://ncbi.nlm.nih.gov/pubmed/18433472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-42
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