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Poly(ADP-Ribose) Polymerase-1 Enhances Transcription of the Profibrotic CCN2 Gene

In the fibrotic kidney, tubular epithelial cells express CCN2, formerly known as connective tissue growth factor. Because little is known about the transcriptional regulation of this profibrotic protein, this study investigated the mechanism underlying epithelial cell–selective upregulation of CCN2...

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Detalhes bibliográficos
Main Authors: Okada, Hirokazu, Inoue, Tsutomu, Kikuta, Tomohiro, Kato, Nobutaka, Kanno, Yoshihiko, Hirosawa, Narumi, Sakamoto, Yasushi, Sugaya, Takeshi, Suzuki, Hiromichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386718/
https://ncbi.nlm.nih.gov/pubmed/18287562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007060648
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