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Oestrogen-mediated cardioprotection following ischaemia and reperfusion is mimicked by an oestrogen receptor (ER)α agonist and unaffected by an ERβ antagonist

Oestrogen protects the heart from ischaemic injury. The current study aims to characterise two novel oestrogen receptor (ER) ligands, an ERα agonist ERA-45 and an ERβ antagonist ERB-88, and then use them to investigate the roles of ERα and ERβ in mediating the cardioprotection by E from ischaemia–re...

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Detalhes bibliográficos
Main Authors: Jeanes, Helen L, Tabor, Caroline, Black, Darcey, Ederveen, Antwan, Gray, Gillian A
Formato: Artigo
Idioma:Inglês
Publicado em: BioScientifica 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386536/
https://ncbi.nlm.nih.gov/pubmed/18492815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-08-0071
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