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An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptimal folding solutions

BACKGROUND: RNAmute is an interactive Java application which, given an RNA sequence, calculates the secondary structure of all single point mutations and organizes them into categories according to their similarity to the predicted structure of the wild type. The secondary structure predictions are...

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Detalhes bibliográficos
Main Authors: Churkin, Alexander, Barash, Danny
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386494/
https://ncbi.nlm.nih.gov/pubmed/18445289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-222
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