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An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptimal folding solutions

BACKGROUND: RNAmute is an interactive Java application which, given an RNA sequence, calculates the secondary structure of all single point mutations and organizes them into categories according to their similarity to the predicted structure of the wild type. The secondary structure predictions are...

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Bibliografiske detaljer
Main Authors: Churkin, Alexander, Barash, Danny
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386494/
https://ncbi.nlm.nih.gov/pubmed/18445289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-222
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