Endotoxin receptor CD14 in PiZ α-1-antitrypsin deficiency individuals

BACKGROUND: CD14, a receptor for lipopolysaccharides (LPS), is found in both a membrane-bound form (mCD14) and a soluble form (sCD14). It is suggested that sCD14 is mainly released from blood monocytes by serine protease-mediated shedding. Because α(1)-antitrypsin (AAT), an inhibitor of serine prote...

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Bibliographic Details
Main Authors: Sandström, Caroline S, Novoradovskaya, Natalia, Cilio, Corrado M, Piitulainen, Eeva, Sveger, Tomas, Janciauskiene, Sabina
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386460/
https://ncbi.nlm.nih.gov/pubmed/18426570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-34
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