Activation of Estrogen Receptor-α by E2 or EGF Induces Temporally Distinct Patterns of Large-Scale Chromatin Modification and mRNA Transcription

Estrogen receptor-α (ER) transcription function is regulated in a ligand-dependent (e.g., estradiol, E2) or ligand-independent (e.g., growth factors) manner. Our laboratory seeks to understand these two modes of action. Using a cell line that contains a visible prolactin enhancer/promoter array (PRL...

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Detalhes bibliográficos
Main Authors: Berno, Valeria, Amazit, Larbi, Hinojos, Cruz, Zhong, Jeannie, Mancini, Maureen G., Dave Sharp, Zelton, Mancini, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386239/
https://ncbi.nlm.nih.gov/pubmed/18509470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002286
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