Similar prevalence of founder BRCA1 and BRCA2 mutations among Ashkenazi and Non-Ashkenazi men with breast cancer: Evidence from 261 cases in Israel, 1976-1999

To evaluate the potential contribution of mutations in the BRCA1 and BRCA2 genes to male breast cancer (MBC), we expanded a previous study to screen a total of 261 Israeli men diagnosed with breast carcinoma. A total of 21 BRCA2 6174delT and eight BRCA1 185delAG mutations were found. Similar frequen...

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Bibliographic Details
Main Authors: Chodick, Gabriel, Struewing, Jeffery P., Ron, Elaine, Rutter, Joni L., Iscovich, Jose
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386175/
https://ncbi.nlm.nih.gov/pubmed/18158280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmg.2007.11.001
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