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Similar prevalence of founder BRCA1 and BRCA2 mutations among Ashkenazi and Non-Ashkenazi men with breast cancer: Evidence from 261 cases in Israel, 1976-1999
To evaluate the potential contribution of mutations in the BRCA1 and BRCA2 genes to male breast cancer (MBC), we expanded a previous study to screen a total of 261 Israeli men diagnosed with breast carcinoma. A total of 21 BRCA2 6174delT and eight BRCA1 185delAG mutations were found. Similar frequen...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2386175/ https://ncbi.nlm.nih.gov/pubmed/18158280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmg.2007.11.001 |
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