Enhancement of Both Long-Term Depression Induction and Optokinetic Response Adaptation in Mice Lacking Delphilin

In the cerebellum, Delphilin is expressed selectively in Purkinje cells (PCs) and is localized exclusively at parallel fiber (PF) synapses, where it interacts with glutamate receptor (GluR) δ2 that is essential for long-term depression (LTD), motor learning and cerebellar wiring. Delphilin ablation...

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Detalhes bibliográficos
Main Authors: Takeuchi, Tomonori, Ohtsuki, Gen, Yoshida, Takashi, Fukaya, Masahiro, Wainai, Tasuku, Yamashita, Manami, Yamazaki, Yoshito, Mori, Hisashi, Sakimura, Kenji, Kawamoto, Susumu, Watanabe, Masahiko, Hirano, Tomoo, Mishina, Masayoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386150/
https://ncbi.nlm.nih.gov/pubmed/18509461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002297
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