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Selection of thermodynamic models for combinatorial control of multiple transcription factors in early differentiation of embryonic stem cells

BACKGROUND: Transcription factors (TFs) have multiple combinatorial forms to regulate the transcription of a target gene. For example, one TF can help another TF to stabilize onto regulatory DNA sequence and the other TF may attract RNA polymerase (RNAP) to start transcription; alternatively, two TF...

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Autors principals: Chen, Chieh-Chun, Zhu, Xin-Guang, Zhong, Sheng
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386060/
https://ncbi.nlm.nih.gov/pubmed/18366607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-S1-S18
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