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Efficacy of nonviral gene transfer in the canine brain

OBJECT: The purpose of this study was to evaluate the gene transfer capability and tolerability of plasmid DNA/polyethylenimine (PEI) complexes in comparison with adenovirus and naked plasmid DNA in the canine brain. METHODS: Plasmid or adenoviral vectors encoding firefly luciferase were injected di...

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Detalhes bibliográficos
Main Authors: Oh, Seunguk, Elizabeth Pluhar, G., Mcneil, Elizabeth A., Kroeger, Kurt M., Liu, Chunyan, Castro, Maria G., Lowenstein, Pedro R., Freese, Andrew, Ohlfest, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384235/
https://ncbi.nlm.nih.gov/pubmed/17639883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/JNS-07/07/0136
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