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Immunization with non-replicating E. coli minicells delivering both protein antigen and DNA protects mice from lethal challenge with lymphocytic choriomeningitis virus

In the midst of new investigations into the mechanisms of both delivery and protection of new vaccines and vaccine carriers, it has become clear that immunization with delivery mechanisms that do not involve living, replicating organisms are vastly preferred. In this report, non-replicating bacteria...

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Autors principals: Giacalone, Matthew J., Zapata, Juan C., Berkley, Neil L., Sabbadini, Roger A., Chu, Yen-Lin, Salvato, Maria S., McGuire, Kathleen L.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384231/
https://ncbi.nlm.nih.gov/pubmed/17258845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2006.11.069
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