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Loss of Gli3 enhances the viability of embryonic telencephalic cells in vitro

The transcription factor Gli3 is important for brain and limb development. Mice homozygous for a mutation in Gli3 (Gli3(Xt/Xt)) have severe abnormalities of telencephalic development and previous studies have suggested that aberrant cell death may contribute to the Gli3(Xt/Xt) phenotype. We demonstr...

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Autors principals: Zaki, Paulette A., Martynoga, Ben, Delafield-Butt, Jonathan T., Fotaki, Vassiliki, Yu, Tian, Price, David J.
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384162/
https://ncbi.nlm.nih.gov/pubmed/16190908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2005.04323.x
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