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Unprecedented diversity of genotypic revertants in lymphocytes of a patient with Wiskott-Aldrich syndrome

Spontaneous somatic reversions of inherited mutations are poorly understood phenomena that are thought to occur uncommonly in a variety of genetic disorders. When molecularly characterized, revertant cells have rarely exhibited more than one revertant genotype per patient. We analyzed individual all...

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Bibliografiske detaljer
Main Authors: Davis, Brian R., DiCola, Michael J., Prokopishyn, Nicole L., Rosenberg, Jonathan B., Moratto, Daniele, Muul, Linda M., Candotti, Fabio, Michael Blaese, R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384133/
https://ncbi.nlm.nih.gov/pubmed/18332229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-06-095299
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