Immunomodulatory effects of plasminogen activators on hepatic fibrogenesis

Tissue-type plasminogen activators (tPA) and urokinase-type plasminogen activators (uPA) are involved in liver repair. We examined the potential immunomodulatory actions of uPA, tPA and uPA-receptor (uPAR) in carbon-tetrachloride-induced hepatic fibrosis in wild-type (WT), tPA(−/−), uPA(−/−) and uPA...

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Detalhes bibliográficos
Main Authors: Higazi, A A, El-Haj, M, Melhem, A, Horani, A, Pappo, O, Alvarez, C E, Muhanna, N, Friedman, S L, Safadi, R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Basic Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384070/
https://ncbi.nlm.nih.gov/pubmed/18279442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03606.x
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