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Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans

The burden of protein misfolding is believed to contribute to aging. However, the links between adaptations to conditions associated with protein misfolding and resistance to the time-dependent attrition of cellular function remain poorly understood. We report that worms lacking aip-1, a homologue o...

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Bibliografische gegevens
Hoofdauteurs: Yun, Chi, Stanhill, Ariel, Yang, Yun, Zhang, Yuhong, Haynes, Cole M., Xu, Chong-Feng, Neubert, Thomas A., Mor, Adam, Philips, Mark R., Ron, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2383958/
https://ncbi.nlm.nih.gov/pubmed/18467495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707025105
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