Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex

BACKGROUND: The reduced folate carrier (RFC1) is an integral membrane protein and facilitative anion exchanger that mediates delivery of 5-methyltetrahydrofolate into mammalian cells. Adequate maternal-fetal transport of folate is necessary for normal embryogenesis. Targeted inactivation of the muri...

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Main Authors: Gelineau-van Waes, Janee, Maddox, Joyce R, Smith, Lynette M, van Waes, Michael, Wilberding, Justin, Eudy, James D, Bauer, Linda K, Finnell, Richard H
格式: Artigo
語言:Inglês
出版: BioMed Central 2008
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2383917/
https://ncbi.nlm.nih.gov/pubmed/18400109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-156
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