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Silent chromatin determines target preference of the Saccharomyces retrotransposon Ty5

The HML and HMR mating loci of Saccharomyces cerevisiae are bound in silent chromatin, which is assembled at the flanking E and I transcriptional silencers. The retrotransposon Ty5 preferentially integrates into regions of silent chromatin, and Ty5 insertions near the HMR-E silencer account for ≈2%...

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Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Zou, Sige, Voytas, Daniel F.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23835/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9207105/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.14.7412
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