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Cloning of a gene (RIG-G) associated with retinoic acid-induced differentiation of acute promyelocytic leukemia cells and representing a new member of a family of interferon-stimulated genes

In a cell line (NB4) derived from a patient with acute promyelocytic leukemia, all-trans-retinoic acid (ATRA) and interferon (IFN) induce the expression of a novel gene we call RIG-G (for retinoic acid-induced gene G). This gene codes for a 58-kDa protein containing 490 amino acids with several pote...

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Detalhes bibliográficos
Main Authors: Yu, Man, Tong, Jian-Hua, Mao, Mao, Kan, Li-Xin, Liu, Meng-Min, Sun, Yi-Wu, Fu, Gang, Jing, Yong-Kui, Yu, Long, Lepaslier, Denis, Lanotte, Michel, Wang, Zhen-Yi, Chen, Zhu, Waxman, Samuel, Wang, Ya-Xin, Tan, Jia-Zhen, Chen, Sai-Juan
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23834/
https://ncbi.nlm.nih.gov/pubmed/9207104
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