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Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development

Glycosylphosphatidylinositol (GPI)-anchored proteins are widely distributed on plasma membranes of eukaryotes. More than 50 GPI-anchored proteins have been shown to be spatiotemporally expressed in mice with a deficiency of GPI-anchor biosynthesis that causes embryonic lethality. Here, we examine th...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Tarutani, Masahito, Itami, Satoshi, Okabe, Masaru, Ikawa, Masahito, Tezuka, Tadashi, Yoshikawa, Kunihiko, Kinoshita, Taroh, Takeda, Junji
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23833/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9207103/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.14.7400
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