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The human T-cell leukemia/lymphotropic virus type I p12I protein cooperates with the E5 oncoprotein of bovine papillomavirus in cell transformation and binds the 16-kilodalton subunit of the vacuolar H+ ATPase.

The human T-cell leukemia/lymphotropic virus type I (HTLV-I) induces T-cell leukemia and transforms human T cells in vitro. A recently identified protein with a molecular weight of 12,000 (12K) (p12I), encoded by single- and double-spliced mRNAs transcribed from the 3' end of the HTLV-I genome, has...

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Published in:J Virol
Main Authors: Franchini, G, Mulloy, J C, Koralnik, I J, Lo Monico, A, Sparkowski, J J, Andresson, T, Goldstein, D J, Schlegel, R
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238245/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8230493/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.12.7701-7704.1993
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