Immunization with the immediate-early tegument protein (open reading frame 62) of varicella-zoster virus protects guinea pigs against virus challenge.

The IE62 protein, the primary regulatory protein of varicella-zoster virus (VZV) and the major component of the virion tegument, was an effective immunogen in the guinea pig model of VZV infection, whereas the ORF 29 gene product, a nonstructural DNA replication protein, did not elicit protection. A...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Sabella, C, Lowry, P W, Abbruzzi, G M, Koropchak, C M, Kinchington, P R, Sadegh-Zadeh, M, Hay, J, Ruyechan, W T, Arvin, A M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238239/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8230489/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.12.7673-7676.1993
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