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In vivo depletion of CD8+ T cells prevents lesions of demyelination in Semliki Forest virus infection.

Following intraperitoneal infection of BALB/c mice with the A7(74) strain of Semliki Forest virus, the virus spreads to the central nervous system (CNS) and initiates an acute inflammatory reaction which includes lesions of primary demyelination. This demyelination is dependent upon activated T lymp...

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Detalhes bibliográficos
Main Authors: Subak-Sharpe, I, Dyson, H, Fazakerley, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC238231/
https://ncbi.nlm.nih.gov/pubmed/7901429
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